SaferWorldbyDesign Webinar: A Novel Framework for Teasing Out Mechanisms of DILI

Tuesday 23 June 2020

16-16:45 CEST - (7 am California, 10 am New York, 3 pm London, 4 pm Zurich, 7:30 pm New Delhi, 11 pm Tokyo)

In this webinar presented by InSphero, Liver Toxicology Team Leader Dr. Monika Kijanska will introduce a framework for mechanistic toxicology investigations, based on a suite of causality assays developed for our 3D InSight™ Liver Toxicology Platform. Monika will discuss how to design experimental programs that help validate relationships between events that trigger toxic responses and identify adverse outcome pathways implicated in drug-induced liver injury, and present example data generated using our liver toxicology platform. You will learn:

  • How one simple, proven causality assay applied using different models at different time points can help tease out mechanisms of DILI
  • How to tune and adapt 3D-optimized causality assays for a wide range of pathways using specific pathway modulators for DILI-specific mechanistic investigations and mechanism based screening
  • Advantages of using a scalable, robust, and versatile 3D in vitro platform for liver toxicology studies.

Presented by a partner of the recently established EU-ToxRisk Commercial Platform for New Approach Methods (NAMs) in Safety Assessment

Latest Tweets

Edelweiss Connect (1 week ago)
Watch our latest #SaferWorldbyDesign panel discussion: In Vitro Biology and Toxicology: Emerging Methods and Best P… https://t.co/cXF7alwRzC
Edelweiss Connect (4 weeks ago)
RT @DanyX23: Great thread about an interactive notebook I recently made about global inequality, recreating a chart in an article by @MaxCR…
Edelweiss Connect (2 months ago)
RT @LabsExplorer: Tomorrow's webinar >> In Vitro Biology and Toxicology: Emerging Methods and Best Practices - by @edelweissconn https://t…
Edelweiss Connect (2 months ago)
Join us for this week's #SaferWorldbyDesign panel webinar and discussion: In Vitro Biology and Toxicology - Emergin… https://t.co/00f76FXSo9
Edelweiss Connect (2 months ago)
RT @barryhardy: Consider meeting with us at the @EU_ToxRisk booth at #2021SOT #ToxExpo to discuss risk assessment supported by integrated t…

Get in touch

  • Address: Edelweiss Connect GmbH
    Technology Park Basel
    Hochbergerstrasse 60C
    CH-4057 Basel / Basel-Stadt
    Switzerland

USA office

  • Address: Edelweiss Connect Inc
    Research Triangle Park NC
    800 Park Offices Dr
    Durham, NC 27709
    USA