EwC News

Since the early 2010s, I have had the opportunity to work alongside the French cosmetics industry through a variety of professional experiences. I first contributed to the French national environmental labelling initiative, developing approaches for assessing the environmental impacts of cosmetic ingredients using the USEtox methodology. More recently, I spent several years supporting manufacturers of cosmetic finished products and raw materials within a private ecotoxicology

We are excited to share the release of our latest preprint on AOPGraphExplorer , now available on bioRxiv. Adverse Outcome Pathways (AOPs) are foundational to mechanistic toxicology and regulatory science; they map how a molecular perturbation can causally lead to an adverse outcome across levels of biological organization. These frameworks help unify and communicate complex mechanistic evidence for chemical risk assessment and safety evaluation. However, AOP knowledge in exi

New Approach Methodologies (NAMs), including in vitro tests, computational models, and in silico tools, are transforming chemical safety assessment. In many cases, the required types of data are widely agreed upon, and this is becoming increasingly clear. What is less clear and (not yet standardized) is how this evidence is collected, combined, and reported within an NGRA (Next Generation Risk Assessment) framework. Many NAM-based assessments still rely on fragmented datase